zoetis zylexis 10*1ml dose

Composition

Inactivated Parapox ovis virus

Indication

For the prevention and treatment of infectious and / or stress -induced diseases, by stimulating the inmune response in dogs, cats, horses, cattle and pigs. In cattle and horses it is indicated for respiratory herpes virus infections, reducing clinical symptoms and virus excretion. In the cat, it has been shown a reduction of clinical symptoms during calicivirus respiratory virus infection. A reduction of clinical symptoms was detected in dogs, cattle and horse during crowding  associated infectious respiratory disease: in pigs suffering from respiratory diseases and in crowding -associated enteric disease ( PWDS ). The stimulation of non-specific immune mechanisms begins rapidly within a few hours to 2 days. The duration of action is about 10 to 14 days after the last injection .

Dosage and administration

- The dose for dogs and cats is 1 ml of the resuspended product, regardless of the age and weight of the animal. Subcutaneous injection

feline herpesvirus-1 (FeHV-1), feline calicivirus (FCV), feline chlamydiosis (feline pneumonitis), feline Bordetella infection, or Feline mycoplasma infection

Packaging 

5 x 1 dose vials of immunomodulator. Rehydrate to 2 mL.
5 x 2 mL vials of sterile diluent.

Background and Objective: High mortalities recorded in diseased cats with Feline panleukopenia virus infection (FPV) and failure of treatment in most of those cases has stimulated us to evaluate different types of treatment used to treat cat with Feline panleukopenia viral infection (FPV) in different ages. Materials and Methods: About 300 cats showing signs suggestive for (FPV) infection were subjected to clinical examination, Rapid enzyme-linked immunosorbent assay (ELISA) on fecal sample to detect viral antigen and blood examination complete blood picture (CBC). Clinical examination revealed the presence of fever, depression, vomiting, diarrhea and dehydration. ELISA on fecal samples was positive for FPV in all the 300 examined cats. Panleukopenia was detected in the examined blood samples. A trail for treatment was applied using supportive classical treatment for all of the diseased cats while 2 groups (each of 100 cats) received also Feliserine Plus and Zylexis as trail for treatment using antibodies specific against FPV and as a source for interferon to control viral infection Results: Recovery rate in the form of clinical improvement and survival of diseased animals were significantly higher in the group treated by Feliserine Plus (85%) followed by the group treated by Zylexis (16.%) in age groups of 6-7, 8-10,12 and 24 months, while sex has no effect using chi-square test. Conclusion: The use of Feline specific neutralizing antibodies against FPV proved to be more efficient in treatment of diseased cats in comparison to the use of inactivated parapox ovis strain D1701, while the use of supportive and classical treatment only gave the lower recovery and survival rate among diseased cats.